There are mainly the following kinds of situations that cause the feeling of something moving at the anal opening: First, parasitic diseases, such as pinworms and other parasitic worms in the anal canal and rectal area, when the worms are active in large numbers or crawl out of the anus to lay eggs, it will be obvious that there is a feeling of worms crawling at the anal opening area, causing strong itching, you can first carry out worm-killing treatment, and disinfection and sterilization of intimate clothing, bed sheets, etc. Second, anal diseases, such as anal sinusitis, perianal eczema, etc., can lead to an increase in local secretions, attached to the anal opening location, causing an obvious itching sensation, while giving patients the illusion that something is wriggling. Anal pruritus as well as anal fissure wound healing period, will also appear similar symptoms, treatment should cause itching of the primary disease to control, will effectively reduce the symptoms. Third, mental illnesses, such as parasitic delusions, can feel parasites crawling all over the body or in a local location, and feel intense itching, it is recommended to go to the psychiatric department for treatment in a timely manner.