Itchy skin after drinking alcohol consider the possibility of alcohol allergy, and the lack of acetaldehyde dehydrogenase in the body, can be quickly relieved through general treatment, topical ointment, oral medication, emergency treatment. 1. General treatment: stop drinking alcohol, mild symptoms can be metabolized by themselves, the more serious symptoms need to promote alcohol metabolism through drugs. 2. Topical medication: If the patient’s skin is only red and itchy after drinking, you can apply some zinc oxide boric acid ointment, fluticasone propionate ointment and so on to relieve the symptoms quickly. 3. Oral medication: If the patient’s skin is red, swollen and itchy over a large area, the itching is severe and the relief effect of ointment is not obvious, the patient can take anti-histamine receptor class of anti-allergy medication orally for treatment. 4. Emergency treatment: If the patient’s skin is red, swollen, hot and itchy, and soon appeared laryngeal edema, dyspnea, shock and other critical phenomena, should be immediately oxygen, intramuscular injection of epinephrine and other rescue. The use of drugs need to follow the doctor’s instructions, if the patient is allergic to alcohol after severe allergies, symptoms immediately after the medical consultation, in order to avoid the emergence of laryngeal edema, respiratory difficulties, shock and other acute allergic reactions.