High anti-thyroglobulin antibodies are not necessarily hypothyroidism. The diagnosis of hypothyroidism mainly needs to look at FT3, FT4, and TSH. The lab tests of hypothyroidism patients usually show a decrease in FT3 and FT4, of which, TSH is elevated in primary hypothyroidism and decreased in central hypothyroidism. Antithyroglobulin antibodies, a common antibody in autoimmune thyroid disease, are secreted by the thyroid gland. He may cause destruction of thyroid tissue and hypothyroidism. However, the presence of hypothyroidism depends mainly on the thyroid hormones FT3 and FT4, and anti-thyroglobulin antibodies are only suggestive and cannot be used as a diagnostic indicator. Therefore, positive antithyroglobulin antibodies are only indicative of autoimmune damage, but cannot confirm hypothyroidism, which is elevated in many autoimmune thyroid disorders, including hyperthyroidism, and therefore cannot be used for diagnosis, but only as an indicator. It is not diagnostic, but only indicative. Prompt medical attention is recommended when positive antithyroglobulin antibodies are detected.