Cranial defects are a common neurosurgical condition, mainly due to some external emergencies and postoperative sequelae of intracranial lesions. For many patients, cranial defects are unfortunate because without the protection of an important barrier on the surface of the brain, the health and safety of a person is always at risk in various aspects. Therefore, cranial repair should be performed as early as possible. Cranial repair is a routine neurosurgical procedure that has been developed for many years and is quite mature. However, there are still many patients who suffer from postoperative problems such as rejection infection, abrasion of the skin, and postoperative unsightliness, mainly because of the different types of surgery chosen. For example, the titanium mesh cranial repair that is widely used in clinical practice may have disadvantages such as rejection infection, material exposure and interference with the impact examination, so patients still need to choose a more advanced and safer repair surgery when they undergo repair. At present, our hospital introduces the new peek cranial repair surgery to perform cranial repair for the majority of patients, and has achieved good results, recognized and praised by patients and their families. It is reported that peek cranial repair is a relatively advanced surgery, this surgery uses peek as cranial repair implant material, unique embedded repair method, material thickness, aperture and groove to make unique design, high comfort, low rate of postoperative rejection infection, and does not affect postoperative MRI and CT examination. At the same time, in order to improve the aesthetic appearance, the surgical design introduces the concept of plastic surgery and further refines the added plastic elements, such as subcutaneous freeing, skin flap transfer, myofascial flap with tip transfer, brow arch shaping, etc., to ensure the symmetry of both sides of the head after surgery and the natural appearance.