Women of childbearing age are at high risk for SLE and are also at high risk for the development of severe lupus. Although SLE is a chronic autoimmune disease with multi-system damage, today, with the development of medical technology, the average survival of patients is much longer than before, and SLE is no longer an incurable disease. SLE can cause varying degrees of damage to multiple organs of the body and can disrupt the physiological functions of multiple systems such as immune, digestive, and hematological, etc. It was once considered a disease with a high mortality rate, and in the 1950s, the 4-year survival rate of SLE patients was only 50%. However, since glucocorticoids and immunosuppressants were used in the treatment of SLE, the situation has greatly improved, and now the 10-year survival rate of SLE patients has reached 90%, and the 15-year survival rate can also reach 80%, and most patients can work and live like normal people under comprehensive and standardized treatment. However, it should be noted that the clinical manifestations of SLE are complex and diverse, and the severity of the disease varies from patient to patient, and the patient’s disease urgency, responsiveness to drugs, living habits and mentality all greatly affect the patient’s prognosis. It is extremely important for patients with lupus to maintain a good attitude and adhere to systematic and standardized treatment. Therefore, for most patients with SLE, regardless of gender, after early diagnosis and systematic and standardized treatment, the prognosis is better and the average survival period is greatly extended.