Chronic renal failure may be related to diabetic nephropathy, hypertensive renal arteriosclerosis, glomerulonephritis (primary and secondary glomerulonephritis), tubulointerstitial diseases (chronic interstitial nephritis, chronic pyelonephritis, uric acid nephropathy, obstructive nephropathy, etc.), renal vascular disease (renal vein thrombosis, etc.), hereditary nephropathies (polycystic kidney disease, hereditary nephritis) and so on. 1. Diabetic nephropathy: chronic renal failure is usually associated with diabetic nephropathy, which will show symptoms such as proteinuria, edema and hypertension. 2. Hypertensive renal microarteriosclerosis: the disease is also known as hypertensive nephropathy, which is asymptomatic at the initial stage, and symptoms such as co-infection, heart failure and anemia will appear in the later stage. 3. Glomerulonephritis: Glomerulonephritis includes both primary and secondary nephritis, usually with symptoms such as edema, proteinuria, anemia, etc., which will lead to chronic renal failure. 4. Tubulointerstitial diseases: these diseases mainly include chronic interstitial nephritis, chronic pyelonephritis, uric acid nephropathy, obstructive nephropathy and so on, which usually lead to chronic renal failure. 5. Renal vascular disease: renal vascular disease is commonly seen in renal vein thrombosis, which is related to the damage of vascular endothelium, the state of blood, such as the speed of blood flow and hypercoagulable state of blood, and will lead to chronic renal failure. 6. Hereditary nephropathy: This kind of disease mainly includes polycystic kidney disease and hereditary nephritis, usually because of genetic defects, which will induce hereditary nephropathy and symptoms of chronic renal failure will appear. Patients with chronic renal failure need to consult a doctor in time to find out the cause and follow the doctor’s instructions.