The incidence of sepsis is high, with more than 18 million cases of severe sepsis worldwide each year and 750,000 cases of sepsis in the United States each year, and this number is increasing at a rate of 1.5% to 8.0% per year. According to statistics, the incidence of sepsis is about 0.3%, and the death rate of sepsis is about 30-40%; the death rate of septic shock is about 50%. The current situation of sepsis incidence and morbidity and mortality rate is more severe, and the morbidity and mortality rate has exceeded that of prostate cancer, breast cancer and AIDS.