Glutathione is found mainly in liver cells and to a lesser extent in heart muscle cells. Glutathione can be examined by blood sampling and is one of the indicators of liver function. When various factors cause damage to liver or cardiac muscle cells, glutathione will be released from the cells into the blood and will show up as an elevation in the blood test, but a single indicator cannot be used to diagnose a physical disease. High glutathione may be a transient change caused by physiological factors, such as staying up late, drinking alcohol or exercising; some hepatotoxic drugs, which can also lead to liver cell damage, manifest as high glutathione, such as anti-tuberculosis drugs, lipid-lowering drugs, antibiotics, etc. In addition, high glutathione cannot exclude disease factors, and different causes of elevated glutathione are handled in different ways: 1. Physiological or Drug factors: if the elevated GTA is caused by staying up late, drinking alcohol or exercising, the elevated GTA is usually not much and there are no other uncomfortable symptoms, so it does not need special treatment and can be recovered after resting; while for liver damage caused by drugs, it is necessary to go to the hospital and reduce or stop using drugs under the guidance of doctors, and liver-protective drugs such as polyphosphocholine can also be added; 2, liver disease factors: for example, viral hepatitis, cirrhosis, alcoholic liver disease, etc. 2, liver disease factors: for example, viral hepatitis, cirrhosis, alcoholic liver disease and other liver diseases lead to liver cell damage, which can cause high glutathione transaminase. Common symptoms of impaired liver function include right upper abdominal pain, anorexia, jaundice, liver palm, spider nevus, etc. The presence of liver injury should also be determined in combination with other examination indicators, such as ghrelin, serum protein, serum bilirubin, etc., as well as liver ultrasound, CT and other examination results. Patients with liver injury can follow the medical prescription for medication, such as tenofovir for antiviral, liver-protective drugs such as reduced glutathione, and anti-yellowing drugs such as rhubarb bile tablets. Those with severely impaired liver function, such as severe jaundice, ascites, hepatic encephalopathy, etc., can undergo liver transplantation; 3. Heart disease factors: the change of glutamic transaminase value is related to the degree and extent of myocardial cell necrosis, and generally the greater the degree and extent of necrosis, the higher the index. High glutamic transaminase may be caused by myocardial infarction or myocarditis. Patients often have symptoms such as chest tightness, chest pain and difficulty in breathing, which need to be combined with cardiac enzymes, cardiac ultrasound, electrocardiogram and other examinations to confirm the diagnosis. Once the diagnosis of heart disease is confirmed, timely treatment is needed, for example, patients with myocardial infarction need to undergo thrombolysis or interventional therapy. In addition, diseases such as dermatomyositis, progressive muscular dystrophy, and crush syndrome may also cause a slight increase in glutathione transaminase, which needs to be treated for clinical symptoms and etiology.