Pruritis ani is a skin disease in which the skin around the anus does not have any primary skin damage but only itchy symptoms, and the disease is more common in 20 to 40 young adults. Male more than female, preferred in the usual inactive people. Clinical manifestations 1, itching is initially limited to the perianal skin itching, paroxysmal, often at night, quiet, emotional changes, diet spicy food, hot and humid exacerbated, heavy itching intolerable. 2, pain, itching is light and heavy, sometimes stinging or burning pain. Due to scratching the skin ulceration, oozing, knotting obsession, long-term. Perianal eczema is a common non-infectious skin disease, lesions are mostly confined to the skin around the anus, and occasionally spread to the buttocks, perineum and clitoris, localized rash, erythema, vesicles, oozing, crusting, flaking. Long course of the disease, the skin around the anus is often thickened, gray or dark red, rough, so that cracking, oozing, itching, recurring as the main features, any age can be onset. Clinical manifestations 1, acute eczema, acute eczema in any part of the general process of redness – papules (maculopapular) – blisters (oozing) – vesicles – crust (scales) – pigmentation of newborn, accompanied by itching. Clinical manifestations of the plasma exudation is obvious, strict cases of dripping exudation, intense itching is difficult to tolerate, scratches, bloody scabs, combined with bacterial infections and pustules, pus oozing, pus crusts, presenting the characteristic appearance of eczema, i.e., the simultaneous existence of multiple types of rashes. Anal skin is a sensitive area, acute eczema itching is particularly intense, fecal contamination is more likely to incur bacterial infection, the symptoms are more serious, can be extended and perineum, scrotum, buttock skin, affecting the patient’s life and work, so that the course of the disease is extremely unstable, prolonging the treatment process, and turn into chronic. 2, chronic eczema, chronic perianal eczema is more common than acute eczema, local manifestations of skin thickening, tinea changes, folds and cracks, tendency to ooze, itching, chronic, easy to recur. 4, subacute eczema from acute eczema inflammation reduction, not timely treatment, delayed for a long time into. Characterized by lesions to small papules, scales and crusts, only a few papules and blisters vesicles. 4, anal contact dermatitis Anal contact dermatitis is also very common in dermatitis, anal contact dermatitis is caused by blood infection, anal contact dermatitis can also be its own infection, anal contact dermatitis has a great relationship with its own cleanliness and the surrounding environment. Anal contact dermatitis is a cellular immune response transmitted through lymphocytes. Clinical manifestations Skin damage is acute, with obvious erythema, edema, papules, and in severe cases, blisters with clear margins, conscious burning itching or pain, and even developing into vesicles, infection, and suppuration.