Lipoma is a common benign tumor with unknown causes, which may be related to genetics and disorders of fat metabolism. They are generally not very harmful to the body. Most of the lipomas on the body surface appear as single elevated masses, which can range in size from a few millimeters to tens of centimeters. The tumors have unchanged skin color on the surface, very soft texture, clear borders, complete envelope, no pressure pain, good mobility, lobulated, and some lobes are very shallow and almost not easy to touch. Treatment is mainly surgical, easy to remove and not easy to recur. Unless it grows in a special area, surgery is usually not very difficult and not very expensive. Most lipomas on the surface of the body can be removed surgically on an outpatient basis without hospitalization. If the surgery goes well, the tumor will come out after the skin is cut open and seen by hand. There is an old lady in Chongqing who was hospitalized because of lipoma in her throat. She was going to have surgery, but before the surgery, she sneezed and the tumor came out. Of course, this is an extreme case, most of them need surgery to get well. Even some patients have serious adhesions between the tumor and the surrounding tissues, which makes the surgery very difficult and takes a long time to remove the tumor completely. This may be related to the rupture of the peritoneum and the spillage of tumor tissue due to the patient’s frequent squeezing. Therefore, it is important not to touch the tumor repeatedly and not to squeeze it, and the doctor should try to be gentle when examining it to prevent squeezing the pericardium and making the surgery more difficult. Nowadays, the surgery of lipoma has entered the era of minimally invasive surgery. Smaller lipomas can be removed by laser with tiny incisions. For larger lipomas, liposuction can be used, in which a small incision is made in the skin and a suction tube is inserted, which can remove the tumor. Minimally invasive surgery is less painful, quicker to recover, and leaves almost no scars, which is especially popular among beauty lovers. Lipoma, like other benign tumors, mostly grows slowly and some of them stop growing after a certain degree, so it does not matter if the surgery is done later or earlier. Small tumors can be left alone if there are no symptoms. However, we still advocate early removal. However, we still advocate early resection because firstly, the diagnosis can be confirmed only after resection and biopsy to prevent misdiagnosis. Secondly, in a few cases, the tumor may be benign at the beginning, but it may become malignant after a long time. Especially, deep lipoma is more likely to be malignant, so it should be removed in time. Thirdly, the smaller the tumor, the easier it is to remove, the shorter the incision, the smaller the scar, the less damage to the beauty, the faster the healing, and the lower the cost. There was an old lady in Guangdong Province who had an egg-sized tumor on her buttocks, and the doctor asked the patient to have it removed surgically. After 20 years, the tumor grew to the size of a soccer and had to be removed at a cost of 2,000 yuan. Although the 20 yuan 20 years ago and the 2,000 yuan 20 years later may be similar, but after all, an egg-sized tumor left in the body for 20 years hatches into a soccer size, which is also scary to think about. There is another kind of multiple lipomas, the etiology, clinical manifestations and treatment are different from single lipoma. Patients have multiple lipomas at the same time or successively, and after a long time, they can grow all over the body with different sizes, and some of them have a slight swelling and pain. It is common in patients with obesity, hyperlipidemia and family history. One or two symptomatic tumors can be removed for pathological examination to confirm the diagnosis, but it is not necessary to remove all of them, and there is no good way to treat them. There is no need to remove all of them, and there is no good treatment. Individual patients can take Chinese medicine effectively, but most of them are ineffective and difficult to cure. It is usually not malignant and not harmful to health. I once treated a man who had a tumor on the back of his shoulder and had it surgically removed in a hospital outpatient clinic. In less than a year, the tumor recurred, and then this doctor removed it for the second time, and the tumor recurred again in less than a year. The third time the patient found the director of the department, the director said, the original resection range is not enough, I will give you personal surgery, cut more, to ensure no recurrence. After resection, no pathological examination was done. Less than a year after the “guarantee”, there was still a recurrence. This time, the patient had a fourth surgery in a foreign country because he was working abroad, and the doctor routinely performed a biopsy on the patient. The result was “liposarcoma”, a malignant tumor similar to cancer. Fortunately, the disease was less malignant and had not metastasized despite all the hardships he had gone through. The patient then underwent radiotherapy in our hospital, and it has been more than 10 years since then, without recurrence and without serious sequelae and complications. So, any tumor must be sent for pathological examination after resection (all surgically resected tissue specimens in human body should be routinely subjected to pathological examination! Including the tissues discharged on their own) to prevent similar misdiagnosis and delayed treatment, leading to adverse consequences.