After the repair of atrial septal defect, attention should be paid to maintaining circulation and observing vital signs, giving respiratory support, in addition to paying attention to diet and life. 1. Pay attention to bed rest, appropriate physical exercise, to avoid venous thrombosis of the lower extremities, but should pay attention to not carry out strenuous physical activities. 2. After the operation, we should pay attention to reasonable diet, a small number of meals, light diet, keep the bowel movement, strengthen the nursing care, to avoid causing infection. 3. Pay attention to taking relevant medications, such as oral aspirin if necessary, to avoid embolism and other situations. 4. Regular follow-up, through the electrocardiogram and other means of detection to clarify the postoperative recovery, to avoid postoperative complications. In conclusion, after atrial surgery, we should pay attention to the vital signs and habits of life, comprehensive management, and if any emergencies occur, we should seek timely and active treatment.