Monkeypox disease is caused by infection with monkeypox virus, and can be intervened by general treatment, symptomatic treatment and medication. 1. General treatment: once diagnosed, isolation should be done; bed rest, avoid strenuous exercise; increase water intake, maintain a balanced dietary nutrition. 2. Symptomatic treatment: This disease can lead to fever, rash, itching and other symptoms. For fever, ice packs can be taken to ice packs and other physical cooling methods to deal with; for the rash, itching, under the guidance of the doctor can be applied to 2% sodium bicarbonate solution and 2% boric acid solution and other drugs for treatment. 3. Drug treatment: for secondary bacterial infection can be given effective antibacterial drug treatment. If infected with monkeypox virus, should seek medical advice as soon as possible, follow the doctor’s instructions for treatment, do not apply drugs arbitrarily, so as not to cause adverse consequences.