Lupus nephritis, generally due to kidney damage caused by systemic lupus erythematosus, is a clinical manifestation of kidney damage in about 80% or more of SLE patients, and kidney biopsy shows kidney involvement of almost 100%. The main clinical manifestations: first, is proteinuria, which is also the most common clinical manifestation of lupus nephritis, the degree of proteinuria varies, some patients show a large amount of albuminuria, some patients show a small amount of proteinuria. The second is hematuria, with microscopic hematuria being more common. Persistent carnitic hematuria or massive microscopic hematuria is mainly seen in patients with glomerular necrosis of capillary collaterals and more crescent formation. Third, is tubular urine, 1/3 of patients have tubular pattern in urine, and it is mainly granular tubular pattern. Fourth, hypertension, some patients with lupus nephritis may have hypertension, and hypertension is related to the degree of kidney lesions. Fifth, is renal failure, if the patient’s condition is not effectively controlled, it may enter into chronic renal failure.