12 years old talking crooked mouth is mainly caused by diseases, common causes include facial nerve paralysis, tumors, cerebral infarction, etc., need to identify the cause of the disease in time after treatment. 1. Facial neuritis: microbial infection, trauma and other factors can induce facial nerve palsy, often divided into central facial nerve palsy and peripheral facial nerve palsy. If there is no timely treatment, the inflammation will affect the sensitivity of the nerves, which will lead to a decrease in the control of facial muscles, showing symptoms such as crooked speech and facial paralysis. 2. Tumor: 12-year-old children with symptoms of crooked mouth may be related to tumor compression, meningioma, acoustic neuroma and other parts of the tumor metastasis may compress the facial nerve, which leads to symptoms of crooked mouth. 3. Cerebral infarction: Cerebral infarction often causes narrowing and occlusion of blood vessels, thus affecting normal blood supply, and in serious cases, it can lead to degeneration and necrosis of brain cells. Patients with cerebral infarction may show symptoms such as facial paralysis, numbness of limbs and crooked mouth. Children should go to the hospital immediately when they feel unwell.