Chronic obstructive pulmonary disease (COPD) has no specific drug. The treatment is mainly divided into the treatment of the stabilization period and the treatment of the acute exacerbation period. 1. Treatment in the stable stage: the most important thing is to persuade smoking cessation; the main treatment for symptom control is the use of bronchodilators such as salbutamol, salmeterol, etc.; glucocorticosteroids such as budesonide can be used in high-risk patients; expectorants such as aminobromine hydrochloride can be used in those who have a lot of sputum that is not easy to be coughed up; and the use of long-term home oxygen therapy can improve the quality of life and the survival rate. 2. Treatment of acute exacerbation: the most important thing is to fight infection and improve respiratory function. Targeted use of anti-bacterial drugs such as penicillin for the cause of acute exacerbation; bronchodilators such as ipratropium bromide; continuous low-flow oxygen inhalation; and glucocorticosteroids such as methylprednisolone can be considered for the treatment of acute exacerbation. Confirmed diagnosis of COPD should be treated systematically under the guidance of professional doctors, and should not use drugs without authorization. Early detection and intervention of COPD is very important.