A large fleshy blockage at the vaginal opening may be a physiological phenomenon or a pathological condition. The possible causes include the following: 1. Labial hypertrophy, which occurs when the vaginal opening is blocked by fleshy blockage due to congenital developmental abnormalities or prolonged local frictional stimulation that leads to hypertrophy of the labia. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things.