Sleeping in the middle of the night hard heart may be caused by heart failure, coronary heart disease, asthma and other causes, different causes of different treatment methods, commonly used treatment methods are drug treatment, surgical treatment. 1. Heart failure: patients can follow the doctor’s advice to use diuretics for treatment, but also follow the doctor’s advice to use beta-receptor antagonists, such as metoprolol, propranolol hydrochloride tablets, etc., but also follow the doctor’s advice to use nitrate drugs for treatment, such as sodium nitroprusside, nitroglycerin, conservative treatment is not obvious, but also follow the doctor’s advice to carry out surgical treatment, such as heart transplantation. 2. Coronary heart disease: patients can be under the guidance of the doctor for antiplatelet therapy, such as aspirin, clopidogrel, etc., but also comply with the doctor’s instructions for the use of antimyocardial ischemic drugs, such as isosorbide nitrate, bisabolol treatment, but also comply with the doctor’s instructions for surgical treatment, such as percutaneous coronary intervention. 3. Asthma: patients may be treated with beta agonists, such as salmeterol, salbutamol, etc., and theophyllines, such as doxophylline, aminophylline, etc., and surgical procedures, such as bronchial thermoplasty, may be prescribed. Other may also be reflux esophagitis and other systemic diseases, the specific treatment also need to go to the hospital to confirm the diagnosis, under the guidance of the doctor to choose, the patient must not be unauthorized use of medication, stop or change medication.