Glucocorticosteroids, commonly used in clinical practice, have significant therapeutic effects despite relatively large side effects, and the use of the drug in general compliance with the doctor’s orders is not terrible, depending on the individual. Glucocorticoids can be used in the treatment of atopic dermatitis, severe bronchial asthma, severe acute infections, acute lymphatic leukemia in children and other diseases. Prolonged application of glucocorticosteroids in high doses may lead to various adverse reactions, such as inducing or exacerbating infections, causing peptic ulcers, delayed wound healing, osteoporosis, muscle atrophy, diabetes mellitus, glaucoma and so on. The dosage and duration of glucocorticosteroids must be done under the guidance of a medical professional. The use of glucocorticosteroids can be life-saving if used appropriately, but may lead to more serious consequences or even life-threatening if not used appropriately. The use of hormones must be standardized, should go to a regular hospital, under the guidance of a professional doctor to use, not unauthorized use.