Patients with hypertension with bilateral renal artery stenosis should not use ACEI and ARB drugs. ACEI drugs commonly used are enalapril, captopril, benazepril, ramipril, etc. ARB drugs commonly used are coxsartan potassium, candesartanate, irbesartan, valsartan, etc. If these drugs are used, it will make the patient’s blood pressure higher, because after using ACEI or ARB drugs will make the patient’s renal intracapsular pressure increases, which raises blood pressure. Patients with renal artery stenosis are recommended to use calcium antagonists, such as nifedipine and amlodipine, in combination with diuretics, such as furosemide, spironolactone, hydrochlorothiazide, and beta-blockers, such as metoprolol tartrate, metoprolol succinate, and bisoprolol. If the blood pressure does not fall satisfactorily after medication, surgical treatment may be considered. All hypertensive patients should undergo renal artery-related examinations to determine whether they have renal artery stenosis in order to guide further treatment options.