Blood cell stings are generally referred to as papular urticaria, a localized skin allergic and inflammatory reaction that occurs when the skin is stung by an insect. Papular urticaria can be recurrent and difficult to eradicate, but symptoms can be controlled with pharmacologic anti-allergy treatments such as oral diphenhydramine and symptomatic treatments such as topical glycerite lotion. Patients with papular urticaria can use medications such as glycerine lotion, compound flumethasone ointment, and halometasone cream under the guidance of a doctor, so as to achieve anti-inflammatory and anti-allergic effects and relieve itching. For patients with localized infections, antibiotic ointments such as mupirocin ointment and erythromycin ointment can also be used for external application. If necessary, follow the doctor’s instructions to take oral loratadine, cetirizine and other drugs, patients with severe allergies, oral prednisone and other glucocorticosteroids. In case of pimple urticaria caused by bee stings, it is necessary to immediately remove the stinger and squeeze out the venom, rinse with water and then apply ice or cold wet compresses locally. For patients with symptoms such as shock, immediate resuscitation treatment by a doctor is needed. Papular urticaria is difficult to eradicate, but after controlling the symptoms through active treatment, it can usually return to normal. Patients should seek timely medical attention and symptomatic treatment under the guidance of a doctor to avoid delaying the condition and causing adverse effects.