Cranial damage is a common and unexpected disease. In neurosurgery, there are few patients with skull damage that require repair. Skull repair is now a relatively routine and constant procedure, and is not as high-risk as many patients may think. Cranial repair surgery itself does not involve brain tissue, so patients who worry about various complications due to brain tissue infection and brain tissue damage are not worried. As long as the surgery is performed in a regular hospital, there will not be various after-effects of improper operation. Skull repair surgery is not complicated. Before surgery, the doctor will shape the repair material selected by the patient according to the results of the MRI, which is an important preoperative preparation. When the patient’s physical condition allows, the surgeon will cut the scalp at a suitable location and bluntly separate the periosteum according to the damaged part, shape and size of the skull. The exposed bone window is clearly visible after hemostasis of the operative field. The surgeon takes the preoperative 3D plasticized bone plate repair piece, adjusts the shape according to the physiological structure of the damaged area, fixes and resets it, and then sutures the scalp layer by layer. A successful skull repair is completed. The ideal material for cranial repair is PEEk, polyether ether ketone PEEK, which provides the ideal repair result. This PEEK polymer material is gradually becoming a new trend in cranial repair materials due to the material’s biocompatibility, ability to be complexly shaped, excellent mechanical properties, good protective properties, and high postoperative comfort. Cranial defects must be cared for according to the postoperative recovery of the affected person. In order to minimize the risk of surgical complications, the postoperative diet should be light and exercise should be performed reasonably, paying particular attention to the care of the wound to avoid other diseases caused by wound infection.