Breast hypoechoic nodule BI-RADS grade 3 found on color ultrasound is commonly found in benign breast lesions, such as verrucous hyperplasia, hyperplastic nodule or adenopathy. If the boundary of the nodule is clear, the shape is regular, and there is no blood flow signal or a small amount of blood flow signal can be seen within the nodule, it needs to be considered as a tumor-like hyperplastic nodule, which belongs to benign lesions, and the breast ultrasound can be rechecked once every six months to one year. If the boundary of the hyperechoic nodule is not clear, and blood flow signal can be seen inside, we need to be alert to the possibility of its further development and deterioration, and it is recommended to review the ultrasound once every three months. If the nodule is found to be significantly enlarged or there is calcification, it is necessary to pay attention to the possibility of breast cancer, in this case, it is recommended to improve the mammogram, and if necessary, to carry out surgical treatment. For women with a family history of breast cancer, ultrasound found that the breast hypoechoic nodule BI-RADS grade 3, need to pay close attention to the changes in the nodule, once there is a malignant tendency should be removed as soon as possible surgery.