Coriolus versicolor and oyster are different in terms of drug source, flavor and attribution, efficacy and action. 1. Origin of medicine: Corrugated seed is the shells of arkshells, mud arkshells or kui arkshells of the family Arcaceae, while oysters are the shells of oysters of the family Ostreaceae, such as the long oyster, the oyster from Dalian Bay or the oyster from the near river. 2. Sexual flavor and meridian: corrugated seed is salty in taste and flat in nature, and belongs to the lung, stomach and liver meridians; oyster is salty in taste and slightly cold in nature, and belongs to the liver, gallbladder and kidney meridians. 3. Efficacy: Corrugated seed has the efficacy of eliminating phlegm and removing blood stasis, softening and dispersing hard lumps, suppressing acidity and relieving pain. It can be used for stubborn phlegm that is sticky and difficult to be clucked, gall tumors (equivalent to thyroid tumors), scrofula (mainly refers to cervical lymph node nodule tuberculosis), mass in the abdomen, lumps, and acidity in stomach pains, etc. It also has a strong calming effect on the mind. Oyster has the efficacy of tranquilizing the mind (using ores and other drugs to stabilize the mind), submerging yang and tonifying yin, and softening hardness and dispersing lumps, and can be used for palpitations and insomnia, dizziness and tinnitus, scrofula and phlegm (lumps swollen up like nuclei under the skin), and masses in the abdomen. The adverse reactions and contraindications of Valeriania are not clear. The contraindications of oyster, which is easy to cause constipation and dyspepsia when taken more than once for a long time, are not clear. The use of medication should be under the guidance of a doctor and is not recommended to be taken at will.