Gastric mucosal leukoplakia is an abnormal lesion of gastric mucosa, which may be caused by physiological factors such as chili peppers as well as pathological factors such as gastric ulcer and atrophic gastritis. 1. Physiological factors: overeating, long-term consumption of spicy hot, ice cream, fried chicken, alcohol, coffee, strong tea, pickles and other spicy and stimulating food, can cause gastric mucosa congestion, edema, erosion and even leukoplakia. 2. Pathologic factors (1) Gastric ulcer: excessive gastric acid secretion, Helicobacter pylori infection and other factors can cause chronic inflammatory reaction of the mucosa, and the emergence of ulcers, leukoplakia-like lesions, causing acid reflux, heartburn, nausea, vomiting and other symptoms. (2) Chronic atrophic gastritis: Helicobacter pylori infection, immunity and other factors can cause gastric mucosal atrophy, glandular less, with or without intestinal epithelial hyperplasia, there can also be leukoplakia-like changes in the gastric mucosa, causing gastric distension, early satiety after meals and other symptoms. Gastric mucosal leukoplakia, it is recommended to consult a doctor for a clear diagnosis and targeted treatment under the guidance of the doctor.