In fact, many patients in the clinic will appear after a heat, the body will be obvious itching, red spots, in fact, this is a kind of urticaria, but this is a special type of urticaria, called cholinergic urticaria. The specific pathogenesis of cholinergic urticaria is not yet clear, but it is believed that its occurrence is often closely related to the patient’s cholinesterase. In the clinic, patients may experience this condition not only when their body temperature is significantly elevated, but also after exercise, emotional excitement or alcohol consumption, or after eating hot food or hot drinks. Some patients simply have itchy, red dots, while others have a typical lesion like a wind cluster, some from childhood, and others only after they have developed the disease and have poor immune resistance.