Multiple small nodules under the pleura of the right lung and under the left lung can be treated with general therapy and medication if they are benign; if they are malignant, surgery or combined radiotherapy and other comprehensive treatments are mostly considered. 1. Benign lesions: If the nodule does not have malignant symptoms such as lobulation, burr and vacuole signs, pleural depression sign, etc., and has benign features such as clear boundary, regular shape and small size (<5mm), it is usually treated by general treatment such as adjusting lifestyle, paying attention to dietary patterns, avoiding spicy and stimulating foods, appropriate exercise, and regular follow-up in the hospital for re-examination. If it is determined that the inflammatory nodules are caused by bacterial infection, cefixime, amoxicillin and other drugs can be taken under the guidance of the doctor for anti-infection treatment. 2. Malignant lesions: If the nodule has lobulation, burr and vacuole sign, pleural depression sign, etc., and the size of the nodule is more than 8mm, it may be malignant tumor, timely bronchoscopy or puncture biopsy, etc., to clarify the nature of the nodule, timely surgical resection and treatment, and if there is no opportunity for surgical treatment, feasible combination of radiotherapy, targeted therapy, and other comprehensive treatment. When patients have multiple small nodules under the pleura of the right lung and under the left lung, they should consult a doctor in time and be treated under the guidance of a doctor.