The very large acne on the face is considered to be nodular or cystic acne, which can be treated with medication, red and blue light therapy and photodynamic surgery. 1. Medication, after the appearance of large acne on the face can be used under the guidance of the doctor medication, commonly used drugs are mainly vinpocetine cream, clindamycin gel, etc., but also with the use of oral medication, such as isotretinoin, doxycycline, tetracycline and so on. 2. Red and blue light treatment, if the acne inflammation is more obvious, red, swollen and painful, you can also choose to carry out red and blue light treatment, by reducing inflammation, relieve the symptoms. 3. Photodynamic therapy, which utilizes photosensitizing drugs (5-amino ketoglutaric acid) to act on the acne area. Through the irradiation of red or yellow light, 5-amino ketoglutaric acid releases singlet oxygen and other substances to kill Propionibacterium acnes and achieve the purpose of treatment. After acne on the face, must actively formal treatment, to avoid aggravation, the formation of cystic nodules, usually need to pay attention to more rest, do a good job of dietary management, light diet.