Patient question: How to adjust the dose of medicine for back pain, pain on both sides of the crotch and spine while taking the medicine? The dose of medicine? Liu wisdom reply: What is the nature of? Is it the pain of long-term a position pressure? If you should not change the paste, the pain is serious is to add a piece of aminophenol oxycodone. Patient question: Hello Dr. Liu, the patient has been in pain this day, we are now using the amount of medicine: tamsulosin hydrochloride extended release capsule 1/day celecoxib capsule 2/day Diosmin tablet 2/day Olanzapine tablet 1/night Flupirtine melitrexin tablet 1/day Premarin capsule 2/day Yesterday added three tablets of oxycodone, today so far used two tablets. How do you think the dosage can be adjusted more appropriately? Patient’s question: Now we still have fenbid, diatriptan and sodium diclofenac in our hands, please see how to adjust our dosage to reduce the symptoms, thank you! Reply: Is it time to change the fentanyl transdermal patch? Patient Question: Hello Dr. Liu: Fentanyl transdermal patch was changed on August 10 at 21:40 pm, and now I have itching and pain in my thighs and two hips and two bones at the back. Liu wisdom reply: If there is no discomfort at present, the next time you change the patch, you can paste 2 patches, if the pain is severe in the past two days, you can temporarily take oral aminophenol oxycodone tablets, up to 4 tablets per day, 1-2 tablets each time. Patient Question: Dr. Liu: Now I have difficulty in getting out of breath, my arms and legs are a bit twitchy, I just took one tablet of aminoglutethimide, my breath is better, my legs are swollen and painful, what do you think? Reply: Is the leg swollen? The pain is divided into many kinds, different pain nature represents different causes, the drug program also varies. If the pain is needle-like, burning-like, consider nerve stimulation, soreness and swelling of the bones generally consider the presence of bone metastases, such as swelling and pain of the extremities with swelling, generally consider vascular compression, poor blood circulation. There are also two different concepts of pain and pain, some of which are needle-like and knife-like pain, while others are soreness, swelling, soreness, numbness and other discomfort. Pain can be relieved by analgesic drugs, but pain (discomfort) analgesic drugs are generally not ideal, the swelling of the lower limbs caused by tumor compression cannot be lifted, then the effect of swelling and pain is not ideal through the use of drugs, which requires the addition of symptomatic treatment with drugs to improve circulation and reduce swelling! Liu wisdom reply: Your loved one also has respiratory difficulty, the opioid dose will affect the breathing, so this is a contradiction point. The first thing you need to clarify is whether it is pain or pain, then you can better guide your medication, pain treatment is comprehensive, adjust the medication at the same time to consider the patient nausea and vomiting, urination and defecation, consciousness and breathing and other complications, to weigh the pros and cons, comprehensive medication.