If your knee hurts from cold, you should rule out any trauma to the knee. If you have had a trauma or a fracture involving the knee joint, it may lead to traumatic arthritis, and the pain may be especially pronounced during weather changes or in humid conditions. It is important to keep the knee warm and to take oral medications such as tianma pills and paralysis capsules to improve the condition. Aseptic inflammation of the knee joint and rheumatoid arthritis may be aggravated by cold or humid conditions. The treatment is the same as for traumatic arthritis. In addition, topical creams can be used, and flurbiprofen gel paste is recommended for its anti-inflammatory and analgesic effects.