Tongue pain may be caused by herpes simplex or herpes zoster, as follows. 1. Herpes simplex: caused by the herpes simplex virus infection, before the blisters can have fever, headache, fatigue and other symptoms, usually clusters of small blisters, like the size of a pinhead, the blisters are thin and easy to break, the formation of irregular vesicles, the patient’s pain is obvious, and can affect the eating and talking. 2. Herpes zoster: caused by varicella-herpes zoster virus infection, herpes dense clusters, ulceration to form a large vesicle, tongue lesions are limited to unilateral, the tongue can be a burning sensation, electric shock-like pain. There may be other causes of tongue pain, it is recommended to go to the hospital in time, clear cause for targeted treatment.