Renal insufficiency may have complications such as anemia, renal bone disease, hypertension, acidosis, cardiovascular and cerebrovascular lesions, coagulation abnormalities, hyperkalemia, and so on. Kidneys can secrete erythropoietin, so renal insufficiency will cause insufficient secretion of erythropoietin and then anemia. In addition, calcium and phosphorus metabolism disorders caused by kidney injury can also cause renal bone disease. Kidneys can excrete excess water, kidney damage, the body’s water discharge is reduced, resulting in an increase in blood volume, causing high blood pressure; but also cause the body’s acid-base balance disorder, resulting in acidosis. Due to the occurrence of high blood pressure and the influence of toxins in the kidneys, it will cause certain damage to blood vessels, which will lead to cardiovascular and cerebrovascular diseases. Chronic renal insufficiency will also cause abnormal blood clotting function, which will easily cause gastrointestinal bleeding. Kidneys have the role of stabilizing the exchange of sodium and potassium ions in the body, and damage can cause hyperkalemia, which in turn inhibits the heartbeat and leads to sudden death. Patients with renal insufficiency need to seek medical treatment in time and follow the doctor’s instructions.