Kidney dialysis is somewhat painful, but most patients can tolerate it. First of all, hemodialysis patients, if they have an arteriovenous fistula as their vascular access, they need to have an arteriovenous fistula puncture every week when they need dialysis, and the nurse will puncture a thicker needle through the arteriovenous fistula to draw blood out of the body, and after the dialysis machine “washes the blood”, the blood will be re-infused into the body. The needle is thicker and the patient may experience pain each time the needle is punctured.2. After the blood is drawn out of the body, the dialysis patient may experience lower blood pressure and discomfort.3. Because of the rapid removal of toxins, this dialysis imbalance syndrome may occur, especially in early patients who have headaches, nausea, vomiting, etc. For patients on peritoneal dialysis, peritoneal dialysis is first of all: i. A peritoneal dialysis cannulation is required, and the procedure is somewhat painful. Second, in addition, after each subsequent dialysis, the peritoneal dialysis fluid is instilled into the abdominal cavity, some patients will feel bloated and uncomfortable, but the majority of them can tolerate it.