Alcohol should be avoided as much as possible when taking antihypertensive drugs. Because most of the drugs, like alcohol, need to be metabolized by the liver and excreted by the kidneys. Drinking alcohol after taking medication will greatly increase the burden on the patient’s liver and kidneys, and may cause great damage to liver function and kidney function. Although some drugs themselves do not have liver and kidney toxicity, drinking alcohol will greatly increase the side effects. Studies have found that the effect of alcohol on the blood pressure of hypertensive patients is characterized by inhibition followed by elevation, resulting in a substantial increase in the fluctuation of blood pressure in hypertensive patients. Excessive fluctuations in blood pressure and abnormally high blood pressure can cause heart attacks and strokes. Drinking alcohol after taking medication for hypertensive patients not only damages the liver, but also can damage kidney function, greatly harming the patient’s cardiovascular system causing huge fluctuations in blood pressure, thus causing blood vessel fluctuations, resulting in thrombotic diseases, making the harm of high blood pressure worse.