The blisters on the body can be considered as chickenpox, contact dermatitis or herpetic epidermolysis bullosa, etc. According to the cause of the disease, we can choose the appropriate treatment measures, such as systematic application of drugs or topical drugs. 1. Chickenpox: isolation of patients is an effective measure to control the spread of the disease, which is self-limiting. Treatment is mainly symptomatic and antiviral, such as symptomatic treatment to reduce fever and itching, and topical medication can be chosen from glycerol lotion; children over 2 years old can choose aciclovir for antiviral treatment. 2. Contact dermatitis: it should be quickly detached from the contact material, find the cause of the disease after symptomatic treatment, under the guidance of the doctor according to the severity of the disease can be taken glucocorticosteroids such as prednisolone or antihistamines such as phenylephrine for treatment, topical glycerine lotion, boric acid solution and other antiseptic. 3. Herpetic epidermolysis bullosa: no specific treatment, symptomatic and supportive treatment, can be used externally with sterile gauze wet dressings, non-adhesive synthetic dressings or antibiotic ointment to prevent and control infections, and if necessary, can be extracted from the blister treatment. Adults can take vitamin E orally, and seriously ill children should be strengthened supportive therapy. The body appears blisters, it is recommended to consult a doctor to identify the cause of the disease, the cause of the symptomatic treatment, the use of medication in accordance with the doctor’s instructions.