Acne on both sides of the nose is considered to be rosacea, acne, folliculitis, etc. It can be eliminated by topical medication, oral medication, and the patient also needs physical elimination. 1. Rosacea: Papular-pustular rosacea is mainly distributed on both sides of the nose, and will appear green bean-sized pimples and pustules. Clindamycin and benzoyl peroxide can be used to reduce the inflammatory lesions. Systemic medications such as oral doxycycline or minocycline and isotretinoin are also usually needed. 2. Acne: Topical application of retinoids, such as adapalene gel and tazarotene gel, and oral retinoids, such as isotretinoin and vincristine, are usually preferred for this condition. Oral doxycycline and minocycline can be taken at the same time when there is an inflammatory response. You can also combine red and blue light irradiation to destroy Propionibacterium acnes and reduce the inflammatory reaction. 3. Folliculitis: Staphylococcus aureus is located on the surface of human skin or nasal mucosa, when the skin and hair follicle areas are damaged, such as around the nose, this situation will appear on both sides of the nose acne symptoms. You can apply compound polymyxin B ointment and clindamycin gel locally, and take itraconazole and cefadroxil orally at the same time if it is serious. Acne on both sides of the nose should go to the hospital in time for examination, according to the results of the comprehensive diagnosis, standardized treatment under the guidance of the doctor, not indiscriminate use of drugs.