Cryptococcal infection of the central nervous system carries a high risk of death, has a very low probability of being cured, and may re-exacerbate even if it goes into remission.
Cryptococcal infections of the central nervous system are often progressive, have a poor prognosis, and have a high mortality rate. Untreated individuals often die within a few months, with a mean duration of illness of 6 months. Complications and neurologic sequelae are also common in treated individuals, with recurrent remissions and exacerbations occurring over several years.
Cryptococcal infections of the central nervous system require prompt medical attention and standardized medication under the guidance of a physician, and the course of treatment is generally longer, with regular monitoring of liver and kidney function, cerebrospinal fluid pressure, routine biochemistry and other relevant indicators.