The causes of sore cheeks are physiologic and pathologic, such as chewing too hard food, parotitis, oral diseases, etc. They can be treated with hot compresses, pain relief and anti-inflammatory. 1. Physiological causes are mainly chewing too hard food or too much chewing action, resulting in pain in the cheek muscles, i.e., sore cheeks, generally do not need special treatment, usually pay attention to eat some soft food, if serious, can be localized hot compresses to alleviate the symptoms. 2. Pathologic causes include mumps, oral diseases, and temporomandibular joint disorders. (1) Mumps is mainly manifested by pain in the cheeks, divided into viral and bacterial, the former can take oral ibuprofen to relieve pain, and at the same time, use ribavirin for antiviral treatment; the latter is mainly staphylococcus aureus and streptococcus infections, and you can use cephalosporins and erythromycin and other antibiotics for anti-inflammatory treatment. (2) Oral diseases such as gingivitis and periodontitis can lead to dental nerve pain, which is manifested as parotid pain, and must be treated under the guidance of a regular dentist. Boric acid solution can be used to sterilize the oral cavity and reduce inflammation, and then oral anti-inflammatory drugs such as amoxicillin and metronidazole are used to relieve the pain. (3) Temporomandibular joint disorders can also lead to soreness in the cheeks, which may be related to external impact, excessive opening of the mouth, jaw biting disorders, etc., and also manifested as difficulty in opening the mouth and chewing limitation, which can be treated with medication, such as ibuprofen and other non-steroidal anti-inflammatory drugs to alleviate the symptoms, glucocorticosteroid injection into the joint cavity, surgery and other treatments. All of the drugs involved above need to be used under the guidance of a doctor and should not be used without authorization.