Creatine phosphate is a kind of high-energy phosphate compound, which is the temporary storage form of high-energy phosphate bond, and can release energy when hydrolyzed, and improve muscle strength when exercising, which is mainly used to reduce myocardial injury and restore normal heart rhythm, and clinically used for myocardial ischemia, myocardial hypertrophy, myocardial infarction, heart failure and other cardiac disorders. Cardiomyopathy patients should pay attention to maintain a good mood, regular work and rest, avoid exertion and late night, appropriate exercise, more walks, gymnastics, playing Tai Chi and other soothing aerobic exercise, avoid strenuous anaerobic exercise, light, less salt diet, not easy to excessively hungry and overfed, so as not to aggravate the burden on the heart. In conclusion, creatine phosphate is a commonly used clinical cardiomyocyte protection agent, which can nourish the myocardium and is mainly used in the treatment of heart disease.