(A) Infectious factors 1, the upper whistle: cold, adenovirus infection, nasal, sinus or tonsillitis, acute and chronic pharyngitis or laryngitis, acute epiglottitis, laryngeal nodules, etc. 2, trachea, bronchial disorders: acute and chronic tracheobronchitis, fine bronchitis, bronchial endotuberculosis, bronchiectasis, etc. 3.Lung and pleural diseases: viral or bacterial pneumonia, mycoplasma, rickettsial or chlamydial pneumonia, pulmonary fungal disease, lung abscess, tuberculosis, lung tumor, pleurisy, etc. 4, infectious diseases, parasitic diseases: measles, pertussis, diphtheria, influenza, leptospirosis, epidemic hemorrhagic fever, pulmonary schistosomiasis, pulmonary encysticercosis, pulmonary amebiasis, acute schistosomiasis, ascariasis, hookworm disease, Pneumocystis carinii, etc. (B) Physical and chemical factors Any lesion that can obstruct, compress or traction the whistle to irritate the wall or distort and narrow the lumen can cause cough. 1, obstruction of the whistle: inhalation of whistle secretions, blood, vomit or other foreign bodies into the whistle, bronchial adenoma or cancer, bronchial stenosis, pulmonary atelectasis, pulmonary edema, emphysema, pulmonary hemorrhage, alveolar microlithosis, idiopathic pulmonary ferritinosis, alveolar proteinosis, mucocutaneous disease, etc. 2, Whistling tract compression: mediastinal tumor or lymph node enlargement, retrosternal thyroid, esophageal cyst, diverticulum or cancer, tuberculosis of hilar or bronchial lymph nodes, pulmonary cyst, pulmonary congestion or bruising, pneumoconiosis, diffuse interstitial pulmonary fibrosis, nodular disease, Wegener’s granulomatosis, radiation pneumonia, pulmonary tumor, cardiomegaly, pericardial effusion, pleural effusion, pneumothorax, pleural tumor, etc. 3, aerosol stimulation inhalation: hot gas or cold air, smoking, inhalation of irritating industrial gases such as chlorine, ammonia, phosgene, ozone, sulfur dioxide, nitrogen oxides or sulfuric acid, nitric acid, formaldehyde and other fog emitted. (iii) Allergic factors Allergic rhinitis, bronchial asthma, exogenous allergic alveolitis, simple pulmonary eosinophilic infiltration, tropical eosinophilia, rheumatic pneumonia, angioneurotic edema, etc. (iv) Others Diaphragmatic hernia, subdiaphragmatic abscess, liver abscess, leukemia, systemic lupus erythematosus, rheumatoid arthritis, scleroderma, polyarteritis nodosa, dermatomyositis, dry syndrome, uremic syndrome, etc.