Vitamin C is a common water-soluble vitamin found in food and is involved in many physiological processes in the body. Vitamin C has been shown to have a potential antioxidant effect on the process of osteoarthritis, and to be a regulatory aid in areas such as cartilage synthesis in the bone and joint. The cartilage matrix contains more than 90% of proteins such as collagen, etc. Vitamin C is an essential cofactor for the synthesis of collagen, hydroxyproline, hydroxylysine, etc. It can play a role in reducing wear and tear of joints and preventing osteoarthritis by binding with bone and collagen. Patients with osteoarthritis should pay attention to the protection of joints in daily life to avoid greater pressure on the joints, eat a balanced diet with more protein, calcium, multivitamins and other nutrients, and seek medical attention in time to clarify the cause of the disease and standardize the treatment if symptoms of discomfort occur.