The diagnosis of hepatocellular carcinoma does not rely on the value of glutamine aminotransferase, and the methods of confirming the diagnosis include taking a history, imaging tests, and pathologic biopsy. Glutaminase is mainly found in liver cells, and when liver cells are damaged, it can be released into the blood in large quantities, resulting in elevated blood concentrations. Its normal value is 0~40U/L, and liver injury is generally considered when it is higher than 40U/L. However, liver injury is not necessarily caused by liver cancer. Viral hepatitis and drug-induced liver injury can also lead to its elevation, and the degree of elevation is proportional to the severity of the disease. Hepatocellular carcinoma is a kind of malignant tumor of liver, which is usually asymptomatic in the early stage, and the clinical manifestations in the late stage may include pain in the liver area, emaciation, fatigue, etc. The auxiliary examination often includes elevated transaminases and masses in the liver, etc. However, its clinical diagnosis is not based on the criteria of liver injury. However, its clinical diagnosis is not based on the criteria of alanine aminotransferase, but rather on the comprehensive judgment based on medical history, alpha-fetoprotein examination, imaging examination and pathological biopsy. Regardless of whether the alanine aminotransferase is too high or liver cancer has been diagnosed, it is recommended to seek medical treatment under the guidance of a doctor.