Men with yellow sperm may be caused by long time without ejaculation, prostatitis, seminal vesiculitis, etc. Patients can be treated by proper sex life or choose to take drugs such as ciprofloxacin and cefuroxime under the guidance of doctors. 1. Long time without ejaculation: the patient’s sperm turning yellow may be related to long-term abstinence and non-ejaculation. Patients can increase the number of ejaculation through appropriate sexual life, which can reduce the phenomenon of yellow sperm. 2. Prostatitis: when the patient suffers from chronic prostatitis, if not effectively treated, it may lead to impaired prostatitis function, affecting the normal play of liquefaction factors, prolonging the time of sperm liquefaction or leading to sperm non-liquefaction, which leads to the phenomenon of yellow semen. Patients can be treated by taking ciprofloxacin, ofloxacin, azithromycin, tamsulosin hydrochloride and other drugs. 3. Spermatitis: when suffering from vesiculitis disease, due to the inflammatory substances in the memory of the seminal vesicles, will be mixed with the semen, which will lead to the yellowing of the sperm, and there may be hematospermia, and ejaculation pain can also occur during ejaculation. Patients can be treated with drugs such as cefuroxime, levofloxacin and isoniazid. It is recommended that men with yellow semen should go to the hospital in time and take effective treatment under the guidance of the doctor. The application of the above drugs should be under the guidance of a specialized physician.