Children’s hand peeling may be due to tinea cruris, eczema, enteropathic telangiectasia and other causes. According to different causes, common clinical treatments include external medication, oral medication, and supplemental trace elements. 1. Tinea cruris: an inflammatory skin disease caused by fungal infection, with blisters, papules, flaking and other symptoms. Parents can follow the doctor’s instructions to give the child external antifungal infection drugs for treatment, such as miconazole nitrate, bifonazole cream, amorphophallus hydrochloride cream, etc.; when the symptoms are serious, follow the doctor’s instructions to take oral terbinafine and other antifungal drugs treatment. 2. Eczema: Eczema on children’s hands can lead to itching, and children scratching leads to peeling of the skin on the hands. Patients can use topical mometasone furoate and other glucocorticoid ointment under the guidance of the doctor to relieve itching symptoms, but also oral loratadine and other antihistamines to stop itching treatment. 3. enteropathic acral dermatitis: zinc deficiency can lead to enteropathic acral dermatitis in children, hands and other parts of the body peeling as one of the common symptoms of the disease. Zinc supplements are needed to treat this condition. Zinc sulfate and zinc gluconate are commonly used in the clinic. These medications should be used in accordance with the doctor’s instructions and should not be used without authorization. There are other causes of hand peeling in children, so it is recommended that parents take their children to the hospital for examination and treatment under the guidance of a professional doctor after a clear diagnosis.