Symptoms of Helicobacter pylori infection include typical symptoms and concomitant symptoms that are mainly characterized by various digestive discomforts. 1. Typical symptoms of various digestive discomforts: (1) Bloating and belching. This is characterized by a feeling of bloating and gas coming up from the stomach, as well as constant burping. (2) Anorexia. This is characterized by loss of appetite, decreased food intake, and intermittent abdominal pain and discomfort. (3) Acid reflux and heartburn. This is characterized by acid flooding up from the stomach and burning discomfort behind the sternum. 2. Accompanying symptoms: (1) Development of peptic ulcer manifesting as chronic periodic rhythmic epigastric pain. (2) The development of gastric cancer is characterized by no specific symptoms in the early stage and weight loss and epigastric pain, vomiting of blood, black stools, anemia, lack of appetite, and fatigue in the progressive stage. At present, the treatment of Helicobacter pylori is mainly a quadruple regimen containing bismuth, i.e., proton pump inhibitor + 2 antibiotics and 1 bismuth, proton pump inhibitor has omeprazole, lansoprazole, etc., antibiotics have clarithromycin, amoxicillin, etc., and bismuth has bismuth potassium citrate, bismuth pectin, etc., with a total of 10-14 days of course of treatment. All of the above medications should be used under doctor’s guidance, avoid self-medication. If diagnosed with Helicobacter pylori infection, early and standardized treatment is recommended to reduce the adverse effects of the disease.