Da Cheng Qi Tang is composed of Rhubarb, Citrus aurantium, Hau Pu, and Mangnit. This formula has the efficacy of clearing down the heat knot, and is mainly used in treating the Yangming Viscera syndrome, the heat knot parasympathetic syndrome, as well as the solid heat syndrome of the internal organs and feverish syncope, spasmodic disease, and frenzy. Dachengqi Tang is composed of rhubarb, citrus aurantium, thick park, and manganese nitrate, and is a representative formula for Yangming visceral syndrome. It has the efficacy of precipitating down the heat knot, and is mainly used for treating Yangming viscera syndrome, with clinical manifestations such as inability to pass stool, abdominal distension, abdominal pain and refusal to be pressed, and even nonsense, hot flashes (a burst of fever), sweating of the hands and feet, and red tongue with yellow and dry fur, etc. This formula can also be used for treating the heat knot in the parietal syndrome. This formula can also be used in the case of Heat-conjunctivitis parvus, which is characterized by discharging foul-smelling water, pure greenish color, and pain in the umbilicus and abdomen. It can also be used in cases of internal solid heat syndrome with febrile convulsions, spasmodic disorders and frenzy. The formula of rhubarb bitter cold diarrhea heat through the bowels, manganese nitrate moist and dry soft, help rhubarb diarrhea through the bowels. Hou Pu moves Qi to remove fullness, and Hovenia Citrus breaks down Qi to remove fullness and eliminate lumps, which can help Rhubarb and Mangnit cleanse the stagnation in the stomach and intestines. The drug is strong in diarrhea and passes through the internal organs, so it should not be used by the elderly, pregnant women, or those with mild heat symptoms. Adverse reactions are not clear. Please use under the guidance of a physician.