The peeling of the hands after chemotherapy may be the hand and foot syndrome caused by chemotherapy, which can be improved by applying moisturizing cream and medication to help. Chemotherapy drugs have certain toxic side effects, which can cause hand-foot syndrome, resulting in peeling of the hands and feet, onychomycosis, nail loss, etc. Depending on the situation, you can take the application of moisturizing creams, anti-infective treatment to improve the program. If the peeling is not very serious, you can apply moisturizing cream and reduce the friction of clothing to improve the condition slowly; if the condition is serious and accompanied by infection, you need to use medication, and if necessary, you can adjust the duration of chemotherapy and the dose of medication. It is recommended that patients with these symptoms seek medical attention and be evaluated by a doctor for appropriate treatment.