The treatment modes of colon cancer with lymph node metastasis for 3 years include surgery, chemotherapy, radiation therapy and so on. When lymph node metastasis occurs in colon cancer, it means that the patient has stage III or stage IV colon cancer, and its treatment principle is to carry out comprehensive treatment mainly based on surgery. 1. Surgery: Surgery is the main treatment method for colon cancer. Generally, radical colon surgery can be used in clinic, i.e. resecting the whole part of the tumor and the intestinal tubes of more than 10cm at the distal and proximal ends, and clearing the nearby lymph nodes. If the patient’s condition is serious, the intestinal tract is completely obstructed, losing the timing of tumor resection, and the physical condition is poor, unable to tolerate major surgery, palliative surgery can also be adopted to improve the quality of life. 2. Chemotherapy: For the above patients with stage III or stage IV colon cancer, adjuvant chemotherapy can be used, specifically FOLFOX regimen, CAPEOX regimen and so on. 3. Radiation therapy: Radiation can kill tumor cells in the irradiation field and play the role of adjuvant therapy. 4. Targeted therapy: Commonly used drugs include bevacizumab, pabolizumab, etc., which is a popular treatment measure at present, and can stimulate the immune ability of human body to achieve a more satisfactory therapeutic effect. When patients have colon cancer symptoms, they need to go to the hospital for treatment as soon as possible to avoid delaying the treatment time.