What medication is used to treat optic nerve papillary edema is related to the cause of the edema. Common causes of optic nerve papillary edema include optic neuritis, ischemic optic neuropathy, and so on. Optic nerve papillary edema is a common symptom in ophthalmology, and any disease that can damage the optic nerve may cause edema, such as inflammation, ischemia, etc. It is necessary to go to the ophthalmology department of the hospital for a detailed funduscopic examination to clarify the specific cause before taking targeted treatment. For edema caused by optic neuritis, it can be treated with glucocorticoid drugs, such as prednisone. For edema caused by ischemic optic neuropathy, glucocorticoids should be used systemically to relieve the symptoms at an early stage, and vasodilating drugs can also be used to improve blood circulation in the optic nerve. Drugs should be used according to the doctor’s prescription. It is recommended that the patient go to the ophthalmology department of a regular hospital to clarify the cause of the disease and follow the doctor’s instructions.