Pleurisy generally can not be self-cured, need to be treated according to the cause. Pleurisy is an inflammation that occurs in the pleural cavity, common tuberculous pleurisy, purulent pleurisy, tumor pleurisy, etc. Clinical manifestations are mainly chest pain, which can be aggravated by breathing and coughing. Pleurisy is not self-limiting and requires active treatment to avoid complications such as sepsis and pleural adhesions. Tuberculous pleurisy requires anti-tuberculosis treatment, such as the use of rifampicin, isoniazid, pyrazinamide, streptomycin and so on. Septic pleurisy is often secondary to bacterial infections such as Streptococcus pneumoniae, Staphylococcus aureus, etc. It can be treated with sensitive antibiotics, such as benzoxacillin, cefixime and azithromycin. Tumor pleurisy is mostly due to the invasion of the pleura by malignant tumors, and needs to be treated against the primary tumor. There are individual differences in the specific treatment modalities, and it is recommended to consult a doctor in a timely manner and follow the doctor’s instructions to use medication, do not wait for the disease to heal itself.