Glutathione is synthesized in the liver and its value often reflects whether or not the liver is damaged and the extent of that damage. The normal value of glutamic oxalacetic transaminase is between 13 and 35 U/L. If glutamic oxalacetic transaminase is below 13 U/L, it is not clinically significant and may be the result of a test error or personal reasons. If the value is significantly lower than the lower limit, it should be taken seriously. There is a condition that can cause low glutathione, such as cirrhosis or liver cancer that can cause severe damage to liver cells, when glutathione is reduced. Low glutathione aminotransferase can also occur at the end stage of the liver, so low glutathione aminotransferase is a serious concern, especially in patients with hepatitis B, cirrhosis or liver tumors, suggesting that the patient is experiencing liver failure, massive hepatocyte necrosis and liver failure.